In order to establish if the antithyroid substance 4(6)-propyl-2-thiouracil (PTU) directly affects the regenerative process of the optic tectum, larval Xenopus laevis at stage 48 (according to Nieuwkoop and Faber, 1956) were submitted to ablation of the right optic lobe and reared in 0.01 % PTU solution. The regenerative process of the optic tectum were compared with controls reared in water. The results obtained demonstrated that the PTU has no direct effect either on the proliferative phase or on the differentiative phase of the regenerative process.
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Con il contributo del Ministero per i Beni e le Attività Culturali