The experiments in this work were designed to study the regenerative capacity of caudal spinal cord in larval Xenopus laevis at stages near to metamorphosis. 70% of the tail was removed in larval Xenopus laevis at stage 56-57 (acc.to Nieuwkoop and Faber, 1956). The experimental animals were reared in 0.01% solution of PTU (4(6)- Propyl-2-thiouracil) in order to inhibit metamorphosis, and sacrificied after 3-5 months. The results obtained demonstrated that: a) the regenerated spinal cord of the tadpoles submitted to amputation of the tail at stage 56-57 presents a histological structure essentially similar to the structure of the regenerated spinal cord of the specimens operated at stage 48. In all cases the regenerated spinal cord is formed by ependymal layer, neurons and fibers, b) PTU has no direct effect on the regenerative process of the caudal spinal cord.
Referenze Bibliografiche
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Con il contributo del Ministero per i Beni e le Attività Culturali