Complexes between pyridoxal-5'-phosphate and different aminocompounds, some of which psychodrugs, have been studied. The variations in the U.V. spectrum of pyridoxal-5'-phosphate are indicated and discussed. The equilibrium constants and the ΔG° of the reactions have been calculated and the kinetics of reactions has been followed. Except for nor-adrenaline and spermine, the behaviour of the aminocompounds is quite similar. Some biological implications are shown.
Referenze Bibliografiche
[1] S. MOUDELES, R. KAPPELMAN e M. E. HANKA (1954) - «J. Biol. Chem.», 209, 397.
[2] W. T. TENKINS e I. W. SIZEN (1960) - «J. Biol. Chem.», 235, 62.
[3] D. A. METZLER e E. E. SNELL (1952) - «J. Am. Chem. Soc.», 74, 979.
[4] D. E. METZLER e E. E. SNELL (1954) - «J. Am. Chem. Soc.», 79, 648.
[5] D. E. METZLER (1956) - «J. Am. Chem. Soc.», 79, 485.
[6] E. E. SNELL (1949) - «J. Am. Chem. Soc.», 67, 194.
[7] D. E. METZLER, J. B. LONGENECKER e E. E. SNELL (1954) - «J. Am. Chem. Soc.», 76, 639.
[8] D. E. METZLER, J. OLIVARD e E. E. SNELL (1954) - «J. Am. Chem. Soc.», 76, 644.
[9] D. E. METZLER, M. IKAWA e E. E. SNELL (1954) - «J. Am. Chem. Soc.», 76, 648.
[10] S. H. SNYDER, J. GLOWINSKI e J. AXELROD (1966) - «J. Pharm, exp. Therap.», 153, 8.
[11] G. KANLSON, E. ROSENGREN e R. THUNBERG (1963) - «J. Physiol.», 169, 467.
[12] R. BUDINI e B. BARBIROLI e A. M. MONTI (1975) - «IRCS», 3, 76.
[13] R. BUDINI, B. BARBIROLI e A. M. MONTI (1975) «IRCS», 3, 77.
[14] J. BLACK (1975) - «Biochem. Pharm.», 20, 924.
[15] H. SATO e G. ZANNONI (1974) - «Biochem. Pharm.», 23, 3121.
[16] H. WADAI e E. E. SNELL (1961) - «J. Biol. Chem.», 236, 2089.
[17] E. FUJIMORI (1959) - «Proc. Nat. Ac. Sc.», 45, 133.
[18] Cz. MASLINSKI, D. KIERSKA e K. KLING (1972) - «Ann. Med. Sect. Pol. Acad. Sci.», 17, 167.
[19] C. J. GRAY (1971) - Enzyme-Catalysed Reactions, Van Nostrand Reinhold, 283.