Fifty larvae of Xenopus laevis at stage 48 (according to Nieuwkoop and Faber) were submitted to tail amputation. Either 50% or 70% of the tail was cut off. The animals were sacrificed from the 30th to the 40th day after the operation, when they had reached stage 56-57. The study of the regenerated tail demonstrated that the histological structure of the neo-formed spinal cord is very similar to that of control animals, although the volume is clearly reduced. The regenerated spinal cord is constituted not only by the ependymal layer but also by the gray periventricular layer; numerous neurons have differentiated, among which the Rohon-Beard nerve cells and the motor neurons are identifiable. The white matter is noticeable, but the Mauthner fibres are lacking. Ganglion cells at the sides of the regenerated spinal cord, approaching its ventral surface, were frequently found.
Referenze Bibliografiche
BAFFONI G. M., «Rend. Acc. Naz. lincei», ser. VIII, 12, 189 (1952).
FILONI S., «Rend. Ist. Sci. Camerino», 5, 111 (1964 a).
FILONI S., «Rend. Acc. Naz. Lincei», ser. III, 37, 521 (1964 b).
FILONI S., «Arch. Ital. Anat. e Embriol.», 74, 89 (1969).
FILONI S. e GIBERTINI G., «Arch. Biol.», 80, 369 (1969).
FILONI S. e MARGOTTA V., «Arch. Ital. Anat. e Embriol.», 75, 171 (1970).
FILONI S. e MARGOTTA V., «Arch. Biol.», 82, 433 (1971)
FILONI S. e MARGOTTA V., «Rend. Acc. Naz. lincei», ser. VIII, 62, 228 (1972).
GOSS R. J., Principles of regeneration, Academic Press, New York and London, 209 (1969).
HOOKER D., «J. Comp. Neur.», 38, 315 (1925).
LORENTE DE NO' R., «Trab. Lab. Invest, biol. Univ. Madr.», 19, 147 (1921).
MARGOTTA V. e FILONI S., «Arch. Biol.», 80, 347 (1969).
MARINESCO G., «C. Rend. Soc. Biol.», 46, 389 (1894).
MARINI M., «Riv. Neurobiol.», 14, 16 (1968).
MARINI M. e BAFFONI G.M., «Rend. Acc. Naz. Lincei», ser. VIII, 42, 943 (1967).
NIEUWKOOP P. D. e FABER J., Normal table of Xenopus laevis (Daudin), Amsterdam: North Holland Publ. Co. (1956).
PIATT J., Regeneration in the central nervous system of Amphibia, in Windle W. F., Regeneration in the central nervous system. Charles C. Thomas, Springfield, 20 (1955).
PIATT J. e PIATT M., «Anat. Rec.», 131, 81 (1958).
ROGUSKI H., «Fol. Biol. (Krakow)», 7, 129 (1959).
SCHÖNHEIT B., «Z. Mikr.-Anat. Forsch.», 72, 519 (1965).
SGOBBO F., «Psichiatria», Napoli, 8, 294 (1890).
STEFANELLI A., «Boll. Soc. Ital. Biol. Sperim.», 19, 252 (1944).
STEFANELLI A., «Rend. Acc. Naz. Lincei», ser. VIII, 8, 498 (1950).
STEFANELLI A., «Boll Zool.», 18, 279 (1951).
STEFANELLI A., «Rend. Acc. Naz. Lincei», ser. VIII, 13, 294 (1952).
STEFANELLI A. e CAPRIATA A., «Ricerche di Morfologia», 20-21, 1 (1943).
STEFANELLI A. e CERVI M., «Boll. Soc. Ital. Biol. Sperim.», 22, 1 (1946).
STEFANELLI A., THERMES G. e MASSIDA R., «Rend. Sem. Fac. Sci. Univ. Cagliari», 20, 1 (1950).
STEFANELLI A., THERMES G. e PODDIE M., «Riv. Biol.», 42, 239 (1950).
THERMES G., «Rend. Sem. Fac. Sci. Univ. Cagliari», 20, 1 (1950).
Con il contributo del Ministero per i Beni e le Attività Culturali