In the present work some physico-chemical properties of human and guinea pig mitochondrial (mit) DNAs are illustrated. The separation of the complementary strands of guinea pig mit DNA in alkaline CsCl and the reassociation kinetics of human mit DNA have been studied. On the basis of the reassociation kinetics data the genetic complexity of human mit DNA has been evaluated: the low complexity of human mit DNA appears to suggest that it contains repeated nucleotide sequences.
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Con il contributo del Ministero per i Beni e le Attività Culturali