Skin fragments (6x4 mm) from adult Triturus marmoratus Latr. were grafted on the dorsal side of adult Triturus cristatus carnifex Laur. The recipient newts were divided into four batches: 1) non-treated (control specimens); 2) X-ray irradiated (1250 r); 3) X-ray irradiated (2450 r); 4) X-ray irradiated (2450 r) and injected with a spleen suspension from the donor. From the results it was apparent that: 1) in non-irradiated allografts an early histoincompatibility reaction develops (day 15); 2) the reject phase is delayed but not prevented by X-ray irradiation; 3) the injection of heterologous spleen from the donor, performed in addition to irradiation, nearly always results in longer survival of the grafts (53 days). On the basis of these results it is suggested that the survival of the graft is due to the formation, in the recipient, of a new lymphoid system at the expense of the lymphocytes from the spleen donor.
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