By the use of a treatment with cytostatic drugs (colchycine, vinblastine sulphate) it was observed that the growth of nerve fibres from chick ganglion cells cultured in vitro is by no means promoted, even when different concentrations were used, by the lack of fibroblast proliferation. Colchycine is capable of blocking the proliferative activity of fibroblastic cells, without hindering the growth of nerve fibres, which goes on in the normal way. Vinblastine, however, in the active concentrations, acts both on the multiplication of fibroblasts and on the growth of nerve fibres.
Referenze Bibliografiche
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Con il contributo del Ministero per i Beni e le Attività Culturali